Research workbench

SH3-guanylate kinase module from psd-95

Analyse SH3-guanylate kinase module from psd-95 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KJW
Type: protein
Length: 292 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Postsynaptic density protein 95
UniProt: P31016
Ligands: SO4
Pockets: 5 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Postsynaptic density protein 95	protein	292	32% helix, 25% strand	P31016

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.66	0.81	42	empty
2	132	0.40	0.74	19	empty
3	122	0.38	0.74	21	empty
4	79	0.33	0.74	18	SO4
5	52	0.26	0.74	15	empty

Compared structures

1KJW · SH3-Guanylate Kinase Module from PSD-95 · the same entry in another collection · chain A against A, TM-score 1.00
P31016 · AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31016
Elsewhere: RCSB PDB 1KJW · PDBe 1KJW · UniProt P31016

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.