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Crystal structure of SRGAP2 F-barx

Analyse Crystal structure of SRGAP2 F-barx in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5I6J
Type: protein
Length: 410 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Slit-robo rho GTPase-activating protein 2
UniProt: O75044
Pockets: 2 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 85% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Slit-robo rho GTPase-activating protein 2	protein	410	85% helix, 0% strand	O75044

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.51	0.84	22	empty
2	65	0.31	0.74	14	empty

Compared structures

5I6J · Crystal Structure of SRGAP2 F-BARx · the same entry in another collection · chain A against A, TM-score 1.00
O75044 · AlphaFold monomer V2.0 prediction for slit-robo rho GTPase-activating protein 2 (O75044) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O75044
Elsewhere: RCSB PDB 5I6J · PDBe 5I6J · UniProt O75044

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