Research workbench
Single chain recombinant globular head of the complement system protein C1Q in complex with magnesium
Analyse Single chain recombinant globular head of the complement system protein C1Q in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5HZF
- Type
- protein
- Length
- 402 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Complement C1Q subcomponent subunit A,COMPLEMENT C1Q subcomponent subunit C,COMPLEMENT…
- UniProt
- P02745, P02747, P02746
- Ligands
- MG
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 1% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Complement C1Q subcomponent subunit A,COMPLEMENT C1Q subcomponent subunit C,COMPLEMENT C1Q subcomponent subunit B | protein | 402 | 1% helix, 55% strand | P02745, P02747, P02746 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 224 | 0.60 | 0.80 | 26 | empty |
| 2 | 83 | 0.48 | 0.83 | 26 | empty |
| 3 | 51 | 0.32 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 5HZF · Single Chain Recombinant Globular Head of the Complement System Protein C1q in complex… · the same entry in another collection · chain A against A, TM-score 1.00
- P02746 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit B (P02746) · a predicted model of the same protein · chain A against A, TM-score 0.38
- P02747 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit C (P02747) · a predicted model of the same protein · chain A against A, TM-score 0.34
- P02745 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit a (P02745) · a predicted model of the same protein · chain A against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02745
- Every structure of UniProt P02747
- Every structure of UniProt P02746
- Elsewhere: RCSB PDB 5HZF · PDBe 5HZF · UniProt P02745 · UniProt P02747 · UniProt P02746
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