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Solution structure of P53TAD-TAZ1

Analyse Solution structure of P53TAD-TAZ1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5HOU
Type: protein
Length: 171 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cellular tumor antigen P53,CREB-binding protein fusion protein
EC: 2.3.1.48
UniProt: P04637, P45481
Ligands: ZN
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 53% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cellular tumor antigen P53,CREB-binding protein fusion protein (EC 2.3.1.48)	protein	171	53% helix, 0% strand	P04637, P45481

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.37	0.77	16	empty

Compared structures

5HOU · Solution Structure of p53TAD-TAZ1 · the same entry in another collection · chain A against A, TM-score 1.00
P45481 · AlphaFold monomer V2.0 prediction for histone lysine acetyltransferase crebbp (P45481) · a predicted model of the same protein · chain A against A, TM-score 0.49

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04637
Every structure of UniProt P45481
Elsewhere: RCSB PDB 5HOU · PDBe 5HOU · UniProt P04637 · UniProt P45481

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