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Crystal structure of elongation factor 2 GDP-form

Analyse Crystal structure of elongation factor 2 GDP-form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5H7K
Type: protein
Length: 367 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Elongation factor 2
UniProt: O59521
Ligands: GDP
Pockets: 2 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Elongation factor 2	protein	367	36% helix, 26% strand	O59521

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.60	0.86	34	empty
2	54	0.35	0.79	15	empty

Compared structures

5H7K · Crystal structure of Elongation factor 2 GDP-form · the same entry in another collection · chain A against A, TM-score 1.00
O59521 · AlphaFold monomer V2.0 prediction for elongation factor 2 (O59521) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O59521
Elsewhere: RCSB PDB 5H7K · PDBe 5H7K · UniProt O59521

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