UniProt O59521
Elongation factor 2 (O59521)
Elongation factor 2 (UniProt O59521): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O59521
- Protein
- Elongation factor 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 37 · 3 records with a druggable one
Structures
7 records of O59521 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5H7J | Crystal structure of Elongation factor 2 | x-ray diffraction | A, B | GCP | 18 (best 0.79) |
| 5H7J | Crystal structure of elongation factor 2 | x-ray diffraction | A, B | — | — |
| 5H7K | Crystal structure of Elongation factor 2 GDP-form | x-ray diffraction | A | GDP | 2 (best 0.60) |
| 5H7K | Crystal structure of elongation factor 2 GDP-form | x-ray diffraction | A | — | — |
| 5H7L | Complex of Elongation factor 2-50S ribosomal protein L12 | x-ray diffraction | A, B | GCP | 17 (best 0.82) |
| 5H7L | Complex of elongation factor 2-50S ribosomal protein L12 | x-ray diffraction | A, B | — | — |
| O59521 | AlphaFold monomer V2.0 prediction for elongation factor 2 (O59521) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5H7K chain A against the predicted model O59521: TM-score 0.96, RMSD 1.40 Å
- 5H7K chain A against the predicted model O59521: TM-score 0.96, RMSD 1.40 Å
- 5H7L chain B against the predicted model O59521: TM-score 0.63, RMSD 5.14 Å
- 5H7L chain B against the predicted model O59521: TM-score 0.63, RMSD 5.14 Å
- 5H7J chain B against the predicted model O59521: TM-score 0.63, RMSD 5.23 Å
- 5H7J chain B against the predicted model O59521: TM-score 0.63, RMSD 5.23 Å
- 5H7L chain A against the predicted model O59521: TM-score 0.62, RMSD 5.05 Å
- 5H7L chain A against the predicted model O59521: TM-score 0.62, RMSD 5.05 Å
- 5H7J chain A against the predicted model O59521: TM-score 0.61, RMSD 5.29 Å
- 5H7J chain A against the predicted model O59521: TM-score 0.61, RMSD 5.29 Å
Elsewhere
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