Research workbench
Imine reductase from aspergillus oryzae
Analyse Imine reductase from aspergillus oryzae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5G6R
- Type
- protein
- Length
- 577 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Imine reductase
- EC
- 1.5.1.48
- UniProt
- Q2TW47
- Ligands
- NDP
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Imine reductase (EC 1.5.1.48) | protein | 288 | 56% helix, 14% strand | Q2TW47 |
| B | Imine reductase (EC 1.5.1.48) | protein | 289 | 57% helix, 14% strand | Q2TW47 |
Ligands and binding sites
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 529 | 0.73 | 0.81 | 45 | NDP |
| 2 | 461 | 0.71 | 0.81 | 50 | NDP |
| 3 | 67 | 0.49 | 0.84 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 4014 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2TW47
- Elsewhere: RCSB PDB 5G6R · PDBe 5G6R · UniProt Q2TW47
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.