Research workbench
Crystal structure of mus musculus protein arginine methyltransferase 2 with sah
Analyse Crystal structure of mus musculus protein arginine methyltransferase 2 with sah in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5FUL
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein arginine N-methyltransferase 2
- EC
- 2.1.1.125
- UniProt
- Q3UKX1
- Ligands
- SAH, CA, CL
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein arginine N-methyltransferase 2 (EC 2.1.1.125) | protein | 339 | 28% helix, 36% strand | Q3UKX1 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- CA · Calcium ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
- PG4 · Tetraethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 403 | 0.74 | 0.84 | 50 | SAH, CA, EDO |
| 2 | 52 | 0.27 | 0.74 | 16 | CL |
Compared structures
- 5FUL · Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with SAH · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3UKX1
- Elsewhere: RCSB PDB 5FUL · PDBe 5FUL · UniProt Q3UKX1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.