UniProt Q3UKX1
Protein arginine N-methyltransferase 2 (Q3UKX1)
Protein arginine N-methyltransferase 2 (UniProt Q3UKX1), EC 2.1.1.125: 11 experimental structures on GenesisL1, 9 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q3UKX1
- Protein
- Protein arginine N-methyltransferase 2
- EC
- 2.1.1.125
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 9 · 7 records with a druggable one
Structures
11 records of Q3UKX1 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FUL | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with SAH | x-ray diffraction | A | SAH, CA, CL | 2 (best 0.74) |
| 5FUL | Crystal structure of mus musculus protein arginine methyltransferase 2 with sah | x-ray diffraction | A | — | — |
| 5FWA | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP1 | x-ray diffraction | A | J7C, CL, CA | 1 (best 0.74) |
| 5FWA | Crystal structure of mus musculus protein arginine methyltransferase 2 with CP1 | x-ray diffraction | A | — | — |
| 5FWD | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP2 | x-ray diffraction | A | GJV, CL, CA | 1 (best 0.73) |
| 5FWD | Crystal structure of mus musculus protein arginine methyltransferase 2 with CP2 | x-ray diffraction | A | — | — |
| 5JMQ | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP3 | x-ray diffraction | A | CA, CL, 6LC | 1 (best 0.73) |
| 5JMQ | Crystal structure of mus musculus protein arginine methyltransferase 2 with CP3 | x-ray diffraction | A | — | — |
| 8BVA | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_114-126 | x-ray diffraction | A | K, QVR | 2 (best 0.73) |
| 8C1J | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30 | x-ray diffraction | A | QVR | 1 (best 0.77) |
| 8PJD | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 94-445 | x-ray diffraction | A | SAH, NA | 1 (best 0.80) |
Ligands
- CA · Calcium ion · in 4 records
- CL · Chloride ion · in 4 records
- QVR · (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol · in 2 records
- SAH · S-adenosyl-L-homocysteine · in 2 records
- 6LC · 9-[(5E)-7-carbamimidamido-5,6,7-trideoxy-beta-D-ribo-hept-5-enofuranosyl]-9H-purin-6-amine · in 1 record
- GJV · 9-(7-{[amino(iminio)methyl]amino}-5,6,7-trideoxy-beta-D-ribo-heptofuranosyl)-9H-purin-6-amine · in 1 record
- J7C · 9-(6-carbamimidamido-5,6-dideoxy-beta-D-ribo-hexofuranosyl)-9H-purin-6-amine · in 1 record
- K · Potassium ion · in 1 record
- NA · Sodium ion · in 1 record
Elsewhere
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