Research workbench

Crystal structure of human defensin-5 Y27A mutant crystal form 1.

Analyse Crystal structure of human defensin-5 Y27A mutant crystal form 1. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5CUM
Type: protein
Length: 96 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Defensin-5
UniProt: Q01523
Ligands: CA, CL

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 59% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Defensin-5	protein	32	0% helix, 59% strand	Q01523

Ligands and binding sites

CA · Calcium ion · metal · chains A, B, C
CL · Chloride ion · ion · 6 copies · chains A, B, C
IPA · Isopropyl alcohol · additive · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

3 interfaces between chains.

A–B · 160 Å² buried · 4 hydrogen bonds · protein-protein
A–C · 160 Å² buried · 4 hydrogen bonds · protein-protein
B–C · 158 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 disulfide (disulfide).

Compared structures

5CUM · Crystal structure of Human Defensin-5 Y27A mutant crystal form 1. · the same entry in another collection · chain A against A, TM-score 1.00
Q01523 · AlphaFold monomer V2.0 prediction for defensin-5 (Q01523) · a predicted model of the same protein · chain C against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01523
Elsewhere: RCSB PDB 5CUM · PDBe 5CUM · UniProt Q01523

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.