UniProt Q01523
Defensin-5 (Q01523)
Defensin-5 (UniProt Q01523): 24 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01523
- Protein
- Defensin-5
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
25 records of Q01523 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZMP | Crystal structure of human defensin-5 | x-ray diffraction | A, C, B, D | — | — |
| 1ZMP | Crystal structure of human defensin-5 | x-ray diffraction | A, C, B, D | — | — |
| 2LXZ | Solution Structure of the Antimicrobial Peptide Human Defensin 5 | solution nmr | A | — | — |
| 2LXZ | Solution structure of the antimicrobial peptide human defensin 5 | solution nmr | A | — | — |
| 2MIT | Solution structure of oxidized dimeric form of human defensin 5 | solution nmr | A, B | — | — |
| 2MIT | Solution structure of oxidized dimeric form of human defensin 5 | solution nmr | A, B | — | — |
| 3I5W | Crystal structure of human alpha-defensin 5 (mutant R13H) | x-ray diffraction | A, B | — | — |
| 3I5W | Crystal structure of human alpha-defensin 5 (mutant R13H) | x-ray diffraction | A, B | — | — |
| 4E82 | Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant) | x-ray diffraction | A, B | — | — |
| 4E82 | Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (GLU21EME mutant) | x-ray diffraction | A, B | — | — |
| 4E83 | Crystal structure of human alpha-defensin 5, HD5 (Leu29NLe mutant) | x-ray diffraction | A, B | — | — |
| 4E83 | Crystal structure of human alpha-defensin 5, HD5 (LEU29NLE mutant) | x-ray diffraction | A, B | — | — |
| 4E86 | Crystal structure of human alpha-defensin 5, HD5 (Leu29Aba mutant) | x-ray diffraction | A, B, C, D, E, F, G, H, L | — | — |
| 4E86 | Crystal structure of human alpha-defensin 5, HD5 (LEU29ABA mutant) | x-ray diffraction | A, B, C, D, E, F, G, H, L | — | — |
| 4RBW | Crystal structure of human alpha-defensin 5, HD5 (Thr7Arg Glu21Arg mutant) | x-ray diffraction | A, B, C, D | — | — |
| 4RBW | Crystal structure of human alpha-defensin 5, HD5 (THR7ARG GLU21ARG mutant) | x-ray diffraction | A, B, C, D | — | — |
| 4RBX | Crystal structure of human alpha-defensin 5, HD5 (Glu21Arg mutant) | x-ray diffraction | A | — | — |
| 4RBX | Crystal structure of human alpha-defensin 5, HD5 (GLU21ARG mutant) | x-ray diffraction | A | — | — |
| 5CUI | Crystal structure of Human Defensin-5 R28A mutant. | x-ray diffraction | A, B, C, D, E, F | CL | 2 (best 0.59) |
| 5CUI | Crystal structure of human defensin-5 R28A mutant. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5CUJ | Crystal structure of Human Defensin-5 Y27A mutant crystal form 2. | x-ray diffraction | A, B, C, D, E, F | CA, CL | 4 (best 0.75) |
| 5CUJ | Crystal structure of human defensin-5 Y27A mutant crystal form 2. | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5CUM | Crystal structure of Human Defensin-5 Y27A mutant crystal form 1. | x-ray diffraction | A, B, C | CA, CL | — |
| 5CUM | Crystal structure of human defensin-5 Y27A mutant crystal form 1. | x-ray diffraction | A, B, C | — | — |
| Q01523 | AlphaFold monomer V2.0 prediction for defensin-5 (Q01523) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1ZMP chain A against the predicted model Q01523: TM-score 0.96, RMSD 0.31 Å
- 1ZMP chain A against the predicted model Q01523: TM-score 0.96, RMSD 0.31 Å
- 4E82 chain A against the predicted model Q01523: TM-score 0.93, RMSD 0.38 Å
- 4E82 chain A against the predicted model Q01523: TM-score 0.93, RMSD 0.39 Å
- 3I5W chain A against the predicted model Q01523: TM-score 0.93, RMSD 0.48 Å
- 3I5W chain A against the predicted model Q01523: TM-score 0.93, RMSD 0.48 Å
- 4E82 chain B against the predicted model Q01523: TM-score 0.93, RMSD 0.41 Å
- 4E82 chain B against the predicted model Q01523: TM-score 0.92, RMSD 0.41 Å
- 4E86 chain L against the predicted model Q01523: TM-score 0.92, RMSD 0.41 Å
- 4E86 chain L against the predicted model Q01523: TM-score 0.92, RMSD 0.41 Å
Elsewhere
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