Research workbench
Structure of BRCA1 brct domains in complex with abraxas single phosphorylated peptide
Analyse Structure of BRCA1 brct domains in complex with abraxas single phosphorylated… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4Y2G
- Type
- protein
- Length
- 221 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Breast cancer type 1 susceptibility protein; BRCA1-a complex subunit abraxas
- EC
- 6.3.2.-
- UniProt
- P38398, Q6UWZ7
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Breast cancer type 1 susceptibility protein (EC 6.3.2.-) | protein | 214 | 36% helix, 19% strand | P38398 |
| B | BRCA1-a complex subunit abraxas | protein | 7 | 0% helix, 14% strand | Q6UWZ7 |
Interfaces
1 interface between chains.
- A–B · 417 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 4Y2G · Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P38398 · AlphaFold monomer V2.0 prediction for breast cancer type 1 susceptibility protein (P38398) · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q6UWZ7 · AlphaFold monomer V2.0 prediction for BRCA1-a complex subunit abraxas 1 (Q6UWZ7) · a predicted model of the same protein · chain B against A, TM-score 0.40
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38398
- Every structure of UniProt Q6UWZ7
- Elsewhere: RCSB PDB 4Y2G · PDBe 4Y2G · UniProt P38398 · UniProt Q6UWZ7
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