UniProt Q6UWZ7
BRCA1-A complex subunit Abraxas (Q6UWZ7)
BRCA1-A complex subunit Abraxas (UniProt Q6UWZ7): 8 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6UWZ7
- Protein
- BRCA1-A complex subunit Abraxas
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
9 records of Q6UWZ7 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4JLU | Crystal structure of BRCA1 BRCT with doubly phosphorylated Abraxas | x-ray diffraction | B | — | — |
| 4JLU | Crystal structure of BRCA1 brct with doubly phosphorylated abraxas | x-ray diffraction | B | — | — |
| 4U4A | Complex Structure of BRCA1 BRCT with singly phospho Abraxas | x-ray diffraction | D, E, F | — | — |
| 4U4A | Complex structure of BRCA1 brct with singly phospho abraxas | x-ray diffraction | D, E, F | — | — |
| 4Y18 | Structure of BRCA1 BRCT domains in complex with Abraxas double phosphorylated peptide | x-ray diffraction | I, J, K, L, M, N, O, P | — | 9 (best 0.78) |
| 4Y18 | Structure of BRCA1 brct domains in complex with abraxas double phosphorylated peptide | x-ray diffraction | I, J, K, L, M, N, O, P | — | — |
| 4Y2G | Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide | x-ray diffraction | B | — | — |
| 4Y2G | Structure of BRCA1 brct domains in complex with abraxas single phosphorylated peptide | x-ray diffraction | B | — | — |
| Q6UWZ7 | AlphaFold monomer V2.0 prediction for BRCA1-a complex subunit abraxas 1 (Q6UWZ7) | predicted | A | — | — |
Experiment against prediction
- 4U4A chain F against the predicted model Q6UWZ7: TM-score 0.58, RMSD 1.20 Å
- 4U4A chain F against the predicted model Q6UWZ7: TM-score 0.58, RMSD 1.20 Å
- 4Y18 chain P against the predicted model Q6UWZ7: TM-score 0.55, RMSD 0.57 Å
- 4Y18 chain P against the predicted model Q6UWZ7: TM-score 0.55, RMSD 0.57 Å
- 4Y18 chain O against the predicted model Q6UWZ7: TM-score 0.52, RMSD 0.75 Å
- 4Y18 chain O against the predicted model Q6UWZ7: TM-score 0.52, RMSD 0.75 Å
- 4Y18 chain N against the predicted model Q6UWZ7: TM-score 0.49, RMSD 0.85 Å
- 4Y18 chain N against the predicted model Q6UWZ7: TM-score 0.49, RMSD 0.85 Å
- 4Y18 chain M against the predicted model Q6UWZ7: TM-score 0.48, RMSD 1.00 Å
- 4Y18 chain M against the predicted model Q6UWZ7: TM-score 0.48, RMSD 1.00 Å
Elsewhere
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