Research workbench
Crystal structure of the high affinity heterodimer of HIF2 alpha and arnt C-terminal pas domains in complex with a tetrazole-containing antagonist
Analyse Crystal structure of the high affinity heterodimer of HIF2 alpha and arnt… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4XT2
- Type
- protein
- Length
- 448 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P27540, Q99814
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 111 | — | P27540 |
| D | — | protein | 107 | — | P27540 |
| A | — | protein | 116 | — | Q99814 |
| C | — | protein | 114 | — | Q99814 |
Compared structures
- 4XT2 · Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS… · the same entry in another collection · chain C against C, TM-score 1.00
- P27540 · AlphaFold monomer V2.0 prediction for aryl hydrocarbon receptor nuclear translocator… · a predicted model of the same protein · chain B against A, TM-score 0.95
- Q99814 · AlphaFold monomer V2.0 prediction for endothelial pas domain- containing protein 1… · a predicted model of the same protein · chain C against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27540
- Every structure of UniProt Q99814
- Elsewhere: RCSB PDB 4XT2 · PDBe 4XT2 · UniProt P27540 · UniProt Q99814
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