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X-ray analysis of a RNA tetraplex R(UGGGGU)4 at ultra-high resolution

Analyse X-ray analysis of a RNA tetraplex R(UGGGGU)4 at ultra-high resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1J8G
Type
RNA
Length
24 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-R(*UP*GP*GP*GP*GP*U)-3'
Ligands
SPM, SR, CA, NA

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D5'-R(*UP*GP*GP*GP*GP*U)-3'rna6——

Ligands and binding sites

  • SPM · Spermine · ligand · chains A, B, C
  • SR · Strontium ion · metal · 8 copies · chains A, B, C, D
  • CA · Calcium ion · metal · 3 copies · chains A, B, C, D
  • NA · Sodium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

6 interfaces between chains.

  • B–D · 324 Ų buried · 14 hydrogen bonds · nucleic-nucleic
  • A–C · 321 Ų buried · 16 hydrogen bonds · nucleic-nucleic
  • C–D · 57 Ų buried · 2 hydrogen bonds · nucleic-nucleic
  • B–C · 55 Ų buried · 0 hydrogen bonds · nucleic-nucleic
  • A–B · 29 Ų buried · 0 hydrogen bonds · nucleic-nucleic

Compared structures

  • 1J8G · X-ray Analysis of a RNA Tetraplex r(uggggu)4 at Ultra-High Resolution · the same entry in another collection · chain C against C, TM-score 1.00

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