Research workbench
Complex structure of ALKB/RHEIN
Analyse Complex structure of ALKB/RHEIN in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4RFR
- Type
- protein
- Length
- 201 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-ketoglutarate-dependent dioxygenase alkb
- EC
- 1.14.11.33
- UniProt
- P05050
- Ligands
- RHN, MN
- Pockets
- 1 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Alpha-ketoglutarate-dependent dioxygenase alkb (EC 1.14.11.33) | protein | 201 | 16% helix, 36% strand | P05050 |
Ligands and binding sites
- RHN · 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid · ligand · chains B
- MN · Manganese (II) ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 262 | 0.69 | 0.84 | 41 | RHN, MN |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05050
- Elsewhere: RCSB PDB 4RFR · PDBe 4RFR · UniProt P05050
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.