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Ligand · RHN

RHN · 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

RHN, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid (C15 H8 O6, 284.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
RHN
Formula
C15 H8 O6
Class
ligand
Structures
6
PDB entries
3

Binding sites

RHN in 6 structures; the first of them:

  • 3R2A · Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and… · RHN A1 · binds ILE268, ASN306, PHE313, ILE324, LEU326, VAL342, ILE345, PHE346 and 2 more
  • 4IE7 · Crystal structure of the human fat mass and obesity associated protein (FTO) in complex… · RHN A602 · binds ILE85, ARG96, TYR106, TYR108, LEU109, LEU203, VAL228, SER229 and 5 more
  • 4RFR · Complex structure of AlkB/rhein · RHN B301 · binds ASN120, TYR122, LEU128, HIS131, ASP133, ILE143, SER145, PHE154 and 9 more
  • 3R2A · Crystal structure of rxralpha ligand-binding domain complexed with corepressor SMRT2 and… · RHN A1 · binds ILE268, ASN306, PHE313, ILE324, LEU326, VAL342, ILE345, PHE346 and 2 more
  • 4IE7 · Crystal structure of the human fat mass and obesity associated protein (fto) in complex… · RHN A602 · binds ILE85, ARG96, TYR106, TYR108, LEU109, LEU203, VAL228, SER229 and 5 more
  • 4RFR · Complex structure of ALKB/RHEIN · RHN B301 · binds ASN120, TYR122, LEU128, HIS131, ASP133, ILE143, SER145, PHE154 and 9 more

Residues it binds most

ILE 8, LEU 8, ARG 4, HIS 6, ASN 6, PHE 6, SER 4, TYR 4, VAL 6, ASP 4 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • ZN · Zinc ion
  • FLC · Citrate anion

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