Research workbench
Crystal structure of TSE3-TSI3 complex
Analyse Crystal structure of TSE3-TSI3 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4N80
- Type
- protein
- Length
- 521 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q9HYC5, Q9HYC4
- Ligands
- CA, ZN
- Pockets
- 3 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 399 | 63% helix, 2% strand | Q9HYC5 |
| B | Uncharacterized protein | protein | 122 | 7% helix, 55% strand | Q9HYC4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 517 | 0.68 | 0.78 | 53 | empty |
| 2 | 147 | 0.40 | 0.74 | 32 | empty |
| 3 | 108 | 0.37 | 0.74 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 1029 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 4N80 · Crystal structure of Tse3-Tsi3 complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HYC4 · AlphaFold monomer V2.0 prediction for immune protein TSI3 (Q9HYC4) · a predicted model of the same protein · chain B against A, TM-score 0.99
- Q9HYC5 · AlphaFold monomer V2.0 prediction for peptidoglycan muramidase TSE3 (Q9HYC5) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HYC5
- Every structure of UniProt Q9HYC4
- Elsewhere: RCSB PDB 4N80 · PDBe 4N80 · UniProt Q9HYC5 · UniProt Q9HYC4
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