Research workbench
Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119
Analyse Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3X0W
- Type
- protein
- Length
- 247 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.71
- Source
- Homo sapiens
- Molecule
- Microtubule-associated proteins 1A/1B light chain 3B
- UniProt
- Q9GZQ8
- Pockets
- 2 · best druggability 0.38
Structure
x-ray diffraction · resolution 2.71 · 2 distinct chains · 32% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microtubule-associated proteins 1A/1B light chain 3B | protein | 124 | 33% helix, 21% strand | Q9GZQ8 |
| B | Microtubule-associated proteins 1A/1B light chain 3B | protein | 123 | 31% helix, 22% strand | Q9GZQ8 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.38 | 0.73 | 23 | empty |
| 2 | 80 | 0.31 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 590 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3X0W · Crystal structure of PLEKHM1 lir-fused human LC3B_2-119 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZQ8 · AlphaFold monomer V2.0 prediction for microtubule-associated proteins 1A/1B light chain… · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZQ8
- Elsewhere: RCSB PDB 3X0W · PDBe 3X0W · UniProt Q9GZQ8
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