UniProt Q9GZQ8
Microtubule-associated proteins 1A/1B light chain 3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (UniProt Q9GZQ8): 73 experimental structures and 1 predicted model on GenesisL1, 24 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9GZQ8
- Protein
- Microtubule-associated proteins 1A/1B light chain 3B
- Experimental structures
- 73
- Predicted models
- 1
- Ligands
- 24
- Pockets
- 43 · 4 records with a druggable one
Structures
74 records of Q9GZQ8 in the MolNFT archive: 73 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1V49 | Solution structure of microtubule-associated protein light chain-3 | solution nmr | A | — | — |
| 1V49 | Solution structure of microtubule-associated protein light chain-3 | solution nmr | A | — | — |
| 2LUE | LC3B OPTN-LIR Ptot complex structure | solution nmr | A | — | — |
| 2LUE | LC3B optn-lir ptot complex structure | solution nmr | A | — | — |
| 2N9X | LC3 FUNDC1 complex structure | solution nmr | A | — | — |
| 2N9X | LC3 FUNDC1 complex structure | solution nmr | A | — | — |
| 2ZJD | Crystal Structure of LC3-p62 complex | x-ray diffraction | A, C | — | — |
| 2ZJD | Crystal structure of LC3-P62 complex | x-ray diffraction | A, C | — | — |
| 3VTU | Crystal structure of human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTU | Crystal structure of human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTV | Crystal structure of Optineurin LIR-fused human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTV | Crystal structure of optineurin lir-fused human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTW | Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 | x-ray diffraction | A, B, C | — | — |
| 3VTW | Crystal structure of T7-tagged optineurin lir-fused human LC3B_2-119 | x-ray diffraction | A, B, C | — | — |
| 3WAO | Crystal structure of Atg13 LIR-fused human LC3B_2-119 | x-ray diffraction | A, B, C, D | — | — |
| 3WAO | Crystal structure of ATG13 lir-fused human LC3B_2-119 | x-ray diffraction | A, B, C, D | — | — |
| 3X0W | Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 | x-ray diffraction | A, B | — | — |
| 3X0W | Crystal structure of PLEKHM1 lir-fused human LC3B_2-119 | x-ray diffraction | A, B | — | — |
| 4WAA | Crystal structure of Nix LIR-fused human LC3B_2-119 | x-ray diffraction | A, B | — | — |
| 4WAA | Crystal structure of nix lir-fused human LC3B_2-119 | x-ray diffraction | A, B | — | — |
| 5D94 | Crystal structure of LC3-LIR peptide complex | x-ray diffraction | A | — | — |
| 5D94 | Crystal structure of LC3-lir peptide complex | x-ray diffraction | A | — | — |
| 5DCN | Crystal structure of LC3 in complex with TECPR2 LIR | x-ray diffraction | A | SO4 | — |
| 5DCN | Crystal structure of LC3 in complex with TECPR2 lir | x-ray diffraction | A | — | — |
| 5GMV | LC3B-FUNDC1 complex | x-ray diffraction | B, A | — | 3 (best 0.70) |
| 5GMV | LC3B-FUNDC1 complex | x-ray diffraction | B, A | — | — |
| 5MS2 | Crystal structure of the Legionella pneumophila effector protein RavZ in complex with human LC3B | x-ray diffraction | B | — | — |
| 5MS2 | Crystal structure of the legionella pneumophila effector protein ravz in complex with human LC3B | x-ray diffraction | B | — | — |
| 5MS5 | Low-salt structure of RavZ LIR2-fused human LC3B | x-ray diffraction | A, B | SO4 | 2 (best 0.44) |
| 5MS5 | Low-salt structure of ravz LIR2-fused human LC3B | x-ray diffraction | A, B | SO4 | — |
| 5MS6 | High-salt structure of RavZ LIR2-fused human LC3B | x-ray diffraction | A, B | — | — |
| 5MS6 | High-salt structure of ravz LIR2-fused human LC3B | x-ray diffraction | A, B | — | — |
| 5V4K | Crystal structure of NEDD4 LIR-fused human LC3B_2-119 | x-ray diffraction | A, B | SO4 | 1 (best 0.27) |
| 5V4K | Crystal structure of NEDD4 lir-fused human LC3B_2-119 | x-ray diffraction | A, B | SO4 | — |
| 5W9A | The structure of the Trim5alpha Bbox- coiled coil in complex LC3B | x-ray diffraction | C, D | — | 6 (best 0.75) |
| 5W9A | The structure of the TRIM5ALPHA bbox- coiled coil in complex LC3B | x-ray diffraction | C, D | — | — |
| 5XAC | CLIR - LC3B | x-ray diffraction | A, B, C, D | — | — |
| 5XAC | CLIR - LC3B | x-ray diffraction | A, B, C, D | — | — |
| 5XAD | NLIR - LC3B fusion protein | x-ray diffraction | A, B | — | — |
| 5XAD | Nlir - LC3B fusion protein | x-ray diffraction | A, B | — | — |
| 5XAE | mutNLIR_LC3B | x-ray diffraction | A, B, C, D | — | 10 (best 0.81) |
| 5XAE | MUTNLIR_LC3B | x-ray diffraction | A, B, C, D | — | — |
| 6J04 | Crystal structure of full length human LC3B delta G120 mutant (2_125) | x-ray diffraction | A, B, C, D | SO4 | — |
| 6J04 | Crystal structure of full length human LC3B delta G120 mutant (2_125) | x-ray diffraction | A, B, C, D | SO4 | — |
| 6LAN | Structure of CCDC50 and LC3B complex | x-ray diffraction | A | — | — |
| 6LAN | Structure of CCDC50 and LC3B complex | x-ray diffraction | A | — | — |
| 7ELG | LC3B modificated with a covalent probe | x-ray diffraction | A | 8Z6, SO4 | 1 (best 0.42) |
| 7ELG | LC3B modificated with a covalent probe | x-ray diffraction | A | 8Z6, SO4 | — |
| 7GA8 | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198158918 | x-ray diffraction | A | K4R, CL | 1 (best 0.33) |
| 7GA9 | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198177230 | x-ray diffraction | A | K6U, CL | — |
| 7GAA | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198233191 | x-ray diffraction | A | K7L, CL | — |
| 7GAB | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1255402624 | x-ray diffraction | A | EYK, CL | 1 (best 0.32) |
| 7GAC | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1456069604 | x-ray diffraction | A | KF8, CL | 1 (best 0.36) |
| 7GAD | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1667545918 | x-ray diffraction | A | K8L, CL | — |
| 7GAE | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1688504114 | x-ray diffraction | A | GV4, CL | — |
| 7GAF | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z183352334 | x-ray diffraction | A | K96, CL | 1 (best 0.32) |
| 7GAG | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z198195770 | x-ray diffraction | A | LJA, CL | 1 (best 0.25) |
| 7GAH | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z2033637875 | x-ray diffraction | A | LRF, CL | 1 (best 0.34) |
| 7GAI | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z212122838 | x-ray diffraction | A | K9N, CL | 1 (best 0.25) |
| 7GAJ | PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z285233820 | x-ray diffraction | A | KB3, CL | — |
14 records more on the page itself.
Ligands
- CL · Chloride ion · in 23 records
- SO4 · Sulfate ion · in 9 records
- 8Z6 · 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione · in 2 records
- 2NU · 2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide · in 1 record
- EYK · 2-tert-butylbenzene-1,4-diol · in 1 record
- GV4 · 2-cyano-~{N}-(1,3,5-trimethylpyrazol-4-yl)ethanamide · in 1 record
- K0J · N-ethyl-1H-1,2,3-triazole-4-carboxamide · in 1 record
- K4R · 1H-indazole-3-carbonitrile · in 1 record
- K6U · (2M)-2-(2-methoxyphenyl)-1,3,4-oxadiazole · in 1 record
- K7L · (4S)-imidazo[1,2-a]pyrimidine-5,7-diol · in 1 record
- K8L · N-[(1,3-thiazol-5-yl)methyl]acetamide · in 1 record
- K96 · N-{[(2R)-oxolan-2-yl]methyl}morpholine-4-carboxamide · in 1 record
- K9N · N-[(4-methyl-1,3-thiazol-2-yl)methyl]cyclobutanecarboxamide · in 1 record
- KA3 · N-(cyclopropylmethyl)-4-methoxypiperidine-1-carboxamide · in 1 record
- KB3 · (5M)-5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-amine · in 1 record
- KBU · 4-chloro-1H-benzimidazole · in 1 record
- KCC · N-methylquinoxalin-2-amine · in 1 record
- KF8 · N-[(3S)-piperidin-3-yl]benzamide · in 1 record
- LJA · N-[3-(carbamoylamino)phenyl]acetamide · in 1 record
- LRF · N~2~-(4-cyano-3-methyl-1,2-thiazol-5-yl)-N~2~-methylglycinamide · in 1 record
- LV4 · 1-[2-(trifluoromethyloxy)phenyl]thiourea · in 1 record
- NUA · N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide · in 1 record
- RV4 · N-{4-[(morpholin-4-yl)methyl]phenyl}acetamide · in 1 record
- RWP · methyl 4-[(trifluoroacetyl)amino]benzoate · in 1 record
Experiment against prediction
- 5GMV chain B against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.74 Å
- 5GMV chain B against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.74 Å
- 5GMV chain A against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.73 Å
- 6J04 chain D against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.73 Å
- 6J04 chain D against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.73 Å
- 6J04 chain A against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.77 Å
- 6J04 chain A against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.77 Å
- 6J04 chain C against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.83 Å
- 6J04 chain C against the predicted model Q9GZQ8: TM-score 0.97, RMSD 0.83 Å
- 6LAN chain A against the predicted model Q9GZQ8: TM-score 0.91, RMSD 0.84 Å
Elsewhere
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