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Solution structure of RIG-I C-terminal domain

Analyse Solution structure of RIG-I C-terminal domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RMJ
Type: protein
Length: 134 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Homo sapiens
Molecule: Probable ATP-dependent RNA helicase DDX58
EC: 3.6.1.-
UniProt: O95786
Pockets: 1 · best druggability 0.37

Structure

solution nmr · resolution NOT · 1 distinct chain · 12% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-)	protein	134	12% helix, 32% strand	O95786

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.37	0.75	21	empty

Compared structures

2RMJ · Solution structure of rig-I C-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
O95786 · AlphaFold monomer V2.0 prediction for antiviral innate immune response receptor rig-I… · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95786
Elsewhere: RCSB PDB 2RMJ · PDBe 2RMJ · UniProt O95786

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