MolNFT v1 · #50576 · protein

Solution structure of rig-I C-terminal domain

2RMJ · Probable ATP-dependent RNA helicase DDX58: “Solution structure of rig-I C-terminal domain”. Solution nmr, 1 pocket (best druggability 0.37). MolNFT v1 #50576 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2RMJ
Type: protein
Length: 134 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable ATP-dependent RNA helicase DDX58
EC: 3.6.1.-
UniProt: O95786
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 12% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-)	protein	134	12% helix, 32% strand	O95786

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.37	0.75	21	empty

Compared structures

2RMJ · Solution structure of RIG-I C-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
O95786 · AlphaFold monomer V2.0 prediction for antiviral innate immune response receptor rig-I… · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95786
Elsewhere: RCSB PDB 2RMJ · PDBe 2RMJ · UniProt O95786

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