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glycosyltransferase

Analyse glycosyltransferase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7W11
Type: protein
Length: 435 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.45
Source: Calotropis gigantea
Molecule: Glycosyltransferase
EC: 2.4.1.-
UniProt: A0A385Z7H9
Ligands: UDP, DTX, GLC
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · resolution 2.45 · 1 distinct chain · 48% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glycosyltransferase (EC 2.4.1.-)	protein	435	48% helix, 17% strand	A0A385Z7H9

Ligands and binding sites

UDP · Uridine-5'-diphosphate · ligand · chains A
DTX · Digitoxigenin · ligand · chains A
GLC · alpha-D-glucopyranose · sugar · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	648	0.78	0.83	64	UDP, GLC, DTX
2	140	0.45	0.77	31	empty

Compared structures

7W11 · Glycosyltransferase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A385Z7H9
Elsewhere: RCSB PDB 7W11 · PDBe 7W11 · UniProt A0A385Z7H9

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