MolNFT v1 · #189866 · protein
Glycosyltransferase
7W11: “Glycosyltransferase”. X-ray diffraction, 3 ligands (UDP, DTX, GLC), 2 pockets (best druggability 0.78). MolNFT v1 #189866 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7W11
- Type
- protein
- Length
- 435 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycosyltransferase
- EC
- 2.4.1.-
- UniProt
- A0A385Z7H9
- Ligands
- UDP, DTX, GLC
- Pockets
- 2 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycosyltransferase (EC 2.4.1.-) | protein | 435 | 48% helix, 17% strand | A0A385Z7H9 |
Ligands and binding sites
- UDP · Uridine-5'-diphosphate · ligand · chains A
- DTX · Digitoxigenin · ligand · chains A
- GLC · alpha-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 648 | 0.78 | 0.83 | 64 | UDP, GLC, DTX |
| 2 | 140 | 0.45 | 0.77 | 31 | empty |
Compared structures
- 7W11 · glycosyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A385Z7H9
- Elsewhere: RCSB PDB 7W11 · PDBe 7W11 · UniProt A0A385Z7H9
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