Research workbench
Flagellar protein FcpB from Leptospira interrogans
Analyse Flagellar protein FcpB from Leptospira interrogans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NQZ
- Type
- protein
- Length
- 421 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.58
- Source
- Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni…
- Molecule
- Flagellar coiling protein B
- UniProt
- Q72RA0
- Ligands
- I3C, IOD
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · resolution 2.58 · 2 distinct chains · 36% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Flagellar coiling protein B | protein | 206 | 38% helix, 28% strand | Q72RA0 |
| B | Flagellar coiling protein B | protein | 215 | 34% helix, 28% strand | Q72RA0 |
Ligands and binding sites
- I3C · 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid · ligand · chains A
- IOD · Iodide ion · ion · 3 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 715 | 0.69 | 0.77 | 78 | GOL, IOD |
| 2 | 269 | 0.58 | 0.78 | 32 | empty |
| 3 | 72 | 0.38 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1656 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6NQZ · Flagellar protein fcpb from leptospira interrogans · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q72RA0
- Elsewhere: RCSB PDB 6NQZ · PDBe 6NQZ · UniProt Q72RA0
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