Research workbench

Human ABCC6 NBD1 H812A in Apo state

Analyse Human ABCC6 NBD1 H812A in Apo state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6NLO
Type: protein
Length: 227 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.85022
Source: Homo sapiens
Molecule: Multidrug resistance-associated protein 6
UniProt: O95255
Ligands: SO4
Pockets: 2 · best druggability 0.41

Structure

x-ray diffraction · resolution 2.85022 · 1 distinct chain · 32% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Multidrug resistance-associated protein 6	protein	227	32% helix, 27% strand	O95255

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.41	0.81	19	empty
2	79	0.37	0.76	17	empty

Compared structures

6NLO · Human ABCC6 NBD1 H812A in apo state · the same entry in another collection · chain A against A, TM-score 1.00
O95255 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 6 (O95255) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95255
Elsewhere: RCSB PDB 6NLO · PDBe 6NLO · UniProt O95255

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.