Research workbench
Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)
Analyse Structural basis for the regulation of inducible nitric oxide synthase (iNOS)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6KEY
- Type
- protein
- Length
- 208 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.24
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- Molecule
- SPRY domain-containing SOCS box protein 2; Nitric oxide synthase, inducible
- EC
- 1.14.13.39
- UniProt
- Q99619, P35228
Structure
x-ray diffraction · resolution 1.24 · 2 distinct chains · 10% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SPRY domain-containing SOCS box protein 2 | protein | 200 | 11% helix, 41% strand | Q99619 |
| B | Nitric oxide synthase, inducible (EC 1.14.13.39) | protein | 8 | 0% helix, 13% strand | P35228 |
Interfaces
1 interface between chains.
- A–B · 365 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 6KEY · Structural basis for the regulation of inducible nitric oxide synthase (inos) by the spry… · the same entry in another collection · chain A against A, TM-score 1.00
- Q99619 · AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 2 (Q99619) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P35228 · AlphaFold monomer V2.0 prediction for nitric oxide synthase, inducible (P35228) · a predicted model of the same protein · chain B against A, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99619
- Every structure of UniProt P35228
- Elsewhere: RCSB PDB 6KEY · PDBe 6KEY · UniProt Q99619 · UniProt P35228
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