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Crystal Structure Analysis of a Eukaryotic Membrane Protein

Analyse Crystal Structure Analysis of a Eukaryotic Membrane Protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IZ0
Type: protein
Length: 224 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.3
Source: Gallus gallus
Molecule: Trimeric intracellular cation channel type A
UniProt: Q5ZK43
Ligands: CA, CL
Pockets: 1 · best druggability 0.64

Structure

x-ray diffraction · resolution 2.3 · 1 distinct chain · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trimeric intracellular cation channel type A	protein	224	78% helix, 0% strand	Q5ZK43

Ligands and binding sites

CA · Calcium ion · metal · chains A
CL · Chloride ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	346	0.64	0.80	36	CL

Compared structures

6IZ0 · Crystal structure analysis of a eukaryotic membrane protein · the same entry in another collection · chain A against A, TM-score 1.00
Q5ZK43 · AlphaFold monomer V2.0 prediction for trimeric intracellular cation channel type a… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5ZK43
Elsewhere: RCSB PDB 6IZ0 · PDBe 6IZ0 · UniProt Q5ZK43

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