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MolNFT v1 · #152960 · protein

Crystal structure analysis of a eukaryotic membrane protein

6IZ0 · Trimeric intracellular cation channel type a: “Crystal structure analysis of a eukaryotic membrane protein”. X-ray diffraction, 2 ligands (CA, CL), 1 pocket (best druggability 0.64). MolNFT v1 #152960 on GenesisL1: 3D structure…

PDB
6IZ0
Type
protein
Length
224 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Trimeric intracellular cation channel type a
UniProt
Q5ZK43
Ligands
CA, CL
Pockets
1 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATrimeric intracellular cation channel type aprotein22478% helix, 0% strandQ5ZK43

Ligands and binding sites

  • CA · Calcium ion · metal · chains A
  • CL · Chloride ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13460.640.8036CL

Compared structures

  • 6IZ0 · Crystal Structure Analysis of a Eukaryotic Membrane Protein · the same entry in another collection · chain A against A, TM-score 1.00
  • Q5ZK43 · AlphaFold monomer V2.0 prediction for trimeric intracellular cation channel type a… · a predicted model of the same protein · chain A against A, TM-score 1.00

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