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Crystal structure of calaxin with calcium

Analyse Crystal structure of calaxin with calcium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5X9A
Type: protein
Length: 386 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.85
Source: Ciona intestinalis
Molecule: Calaxin
UniProt: Q8T893
Ligands: CA
Pockets: 4 · best druggability 0.68

Structure

x-ray diffraction · resolution 1.85 · 2 distinct chains · 67% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calaxin	protein	188	67% helix, 5% strand	Q8T893
B	Calaxin	protein	198	66% helix, 5% strand	Q8T893

Ligands and binding sites

CA · Calcium ion · metal · 7 copies · chains A, B
EDO · 1,2-ethanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	463	0.68	0.79	50	empty
2	366	0.68	0.81	44	empty
3	109	0.46	0.79	18	empty
4	79	0.39	0.78	15	empty

Interfaces

1 interface between chains.

A–B · 955 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

5X9A · Crystal structure of calaxin with calcium · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8T893
Elsewhere: RCSB PDB 5X9A · PDBe 5X9A · UniProt Q8T893

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