GL1X · GenesisL1 explorer

Research workbench

The third PDZ domain from the synaptic protein PSD-95 in complex with a mutant C-terminal peptide derived from CRIPT (T-2F)

Analyse The third PDZ domain from the synaptic protein PSD-95 in complex with a mutant… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5HED
Type
protein
Length
126 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.7
Source
Rattus norvegicus; SYNTHETIC CONSTRUCT
Molecule
Disks large homolog 4; Cysteine-rich PDZ-binding protein
UniProt
P31016, Q792Q4

Structure

x-ray diffraction · resolution 1.7 · 2 distinct chains · 17% helix, 33% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADisks large homolog 4protein11819% helix, 32% strandP31016
BCysteine-rich PDZ-binding proteinprotein80% helix, 50% strandQ792Q4

Interfaces

1 interface between chains.

  • A–B · 585 Ų buried · 16 hydrogen bonds · protein-protein

Compared structures

  • 5HED · The third PDZ domain from the synaptic protein psd-95 in complex with a mutant C-terminal… · the same entry in another collection · chain A against A, TM-score 1.00
  • P31016 · AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016) · a predicted model of the same protein · chain A against A, TM-score 0.81
  • Q792Q4 · AlphaFold monomer V2.0 prediction for cysteine-rich PDZ-binding protein (Q792Q4) · a predicted model of the same protein · chain B against A, TM-score 0.46

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.