Research workbench
AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q5SSZ7)
Analyse AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZNRF3 (Q5SSZ7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5SSZ7
- Type
- protein
- Length
- 913 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- E3 ubiquitin-protein ligase ZNRF3
- UniProt
- Q5SSZ7
- Pockets
- 1 · best druggability 0.47
Structure
1 distinct chain · 11% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase ZNRF3 | protein | 913 | 11% helix, 8% strand | Q5SSZ7 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.47 | 0.84 | 14 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 4CDK · Structure of ZNRF3-RSPO1 · an experimental structure of the same protein · chain A against C, TM-score 0.17
- 4CDK · Structure of ZNRF3-RSPO1 · an experimental structure of the same protein · chain A against C, TM-score 0.17
- 4CDJ · Structure of ZNRF3 ectodomain · an experimental structure of the same protein · chain A against B, TM-score 0.17
- 4CDJ · Structure of ZNRF3 ectodomain · an experimental structure of the same protein · chain A against B, TM-score 0.17
- 4C8A · mouse ZNRF3 ectodomain crystal form II · an experimental structure of the same protein · chain A against C, TM-score 0.17
- 4C8A · Mouse ZNRF3 ectodomain crystal form II · an experimental structure of the same protein · chain A against C, TM-score 0.17
- 4C9E · Mouse ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 (Seleno Met) crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 4C9E · Mouse ZNRF3 ectodomain in complex with xenopus RSPO2 FU1- FU2 (seleno met) crystal form II · an experimental structure of the same protein · chain A against A, TM-score 0.17
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SSZ7
- Elsewhere: UniProt Q5SSZ7 · AlphaFold DB Q5SSZ7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.