Research workbench
AlphaFold monomer V2.0 prediction for protein wntless homolog (Q5T9L3)
Analyse AlphaFold monomer V2.0 prediction for protein wntless homolog (Q5T9L3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5T9L3
- Type
- protein
- Length
- 541 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x556B5F949095C71590D201CC2FbEA0Ca9e5aD1d7
- Molecule
- Protein wntless homolog
- UniProt
- Q5T9L3
- Pockets
- 9 · best druggability 0.86
Structure
1 distinct chain · 50% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein wntless homolog | protein | 541 | 50% helix, 16% strand | Q5T9L3 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 836 | 0.86 | 0.88 | 88 | empty |
| 2 | 907 | 0.80 | 0.82 | 64 | empty |
| 3 | 207 | 0.61 | 0.81 | 26 | empty |
| 4 | 187 | 0.57 | 0.80 | 20 | empty |
| 5 | 108 | 0.53 | 0.83 | 17 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 8TZS · Structure of human WLS · an experimental structure of the same protein · chain A against A, TM-score 0.86
- 8TZO · Structure of human Wnt7a bound to WLS and CALR · an experimental structure of the same protein · chain A against B, TM-score 0.83
- 8TZP · Structure of human Wnt7a bound to WLS and RECK · an experimental structure of the same protein · chain A against B, TM-score 0.83
- 8TZR · Structure of human Wnt3a bound to WLS and CALR · an experimental structure of the same protein · chain A against B, TM-score 0.83
- 7DRT · Human wntless in complex with WNT3A · an experimental structure of the same protein · chain A against B, TM-score 0.83
- 7DRT · Human Wntless in complex with Wnt3a · an experimental structure of the same protein · chain A against B, TM-score 0.83
- 7KC4 · Human WLS in complex with WNT8A · an experimental structure of the same protein · chain A against B, TM-score 0.82
- 7KC4 · Human wls in complex with WNT8A · an experimental structure of the same protein · chain A against B, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5T9L3
- Elsewhere: UniProt Q5T9L3 · AlphaFold DB Q5T9L3
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