Research workbench
AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit a, vacuolar isoform (P32563)
Analyse AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit a, vacuolar… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P32563
- Type
- protein
- Length
- 840 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb4D2d9c96b0D792d0b77e7147D724cc1F801ae58
- Molecule
- V-type proton ATPase subunit a, vacuolar isoform
- UniProt
- P32563
- Pockets
- 11 · best druggability 0.69
Structure
1 distinct chain · 60% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-type proton ATPase subunit a, vacuolar isoform | protein | 840 | 60% helix, 9% strand | P32563 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 228 | 0.69 | 0.86 | 27 | empty |
| 2 | 288 | 0.58 | 0.77 | 33 | empty |
| 3 | 257 | 0.56 | 0.77 | 30 | empty |
| 4 | 202 | 0.54 | 0.78 | 23 | empty |
| 5 | 129 | 0.42 | 0.75 | 22 | empty |
Compared structures
- 7TMT · V-ATPase from Saccharomyces cerevisiae, State 3 · an experimental structure of the same protein · chain A against a, TM-score 0.82
- 8EAU · Yeast VO in complex with Vma21p · an experimental structure of the same protein · chain A against a, TM-score 0.82
- 6PE4 · Yeast vo motor in complex with 1 vopq molecule · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6PE4 · Yeast Vo motor in complex with 1 VopQ molecule · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6PE5 · Yeast vo motor in complex with 2 vopq molecules · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6PE5 · Yeast Vo motor in complex with 2 VopQ molecules · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 7FDA · Cryoem structure of reconstituted V-ATPase, STATE1 · an experimental structure of the same protein · chain A against Q, TM-score 0.81
- 7FDA · CryoEM Structure of Reconstituted V-ATPase, state1 · an experimental structure of the same protein · chain A against Q, TM-score 0.81
- 7TAO · Cryo-EM structure of bafilomycin A1 bound to yeast vo V-ATPase · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 7TAO · Cryo-EM structure of bafilomycin A1 bound to yeast VO V-ATPase · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6M0R · 2.7A yeast vo STATE3 · an experimental structure of the same protein · chain A against A, TM-score 0.81
- 6M0R · 2.7A Yeast Vo state3 · an experimental structure of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32563
- Elsewhere: UniProt P32563 · AlphaFold DB P32563
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