Research workbench
AlphaFold monomer V2.0 prediction for V-type proton ATPase catalytic subunit a (P31404)
Analyse AlphaFold monomer V2.0 prediction for V-type proton ATPase catalytic subunit a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P31404
- Type
- protein
- Length
- 617 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- V-type proton ATPase catalytic subunit a
- UniProt
- P31404
- Pockets
- 10 · best druggability 0.51
Structure
1 distinct chain · 40% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-type proton ATPase catalytic subunit a | protein | 617 | 40% helix, 25% strand | P31404 |
Pockets
10 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 175 | 0.51 | 0.78 | 38 | empty |
| 2 | 59 | 0.47 | 0.84 | 14 | empty |
| 3 | 80 | 0.45 | 0.81 | 19 | empty |
| 4 | 109 | 0.45 | 0.78 | 20 | empty |
| 5 | 157 | 0.40 | 0.73 | 22 | empty |
Compared structures
- 7KHR · Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 7KHR · Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6XBW · Cryo-EM structure of V-ATPase from bovine brain, state 1 · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6XBW · Cryo-EM structure of V-ATPase from bovine brain, state 1 · an experimental structure of the same protein · chain A against C, TM-score 0.96
- 6XBY · Cryo-EM structure of V-ATPase from bovine brain, state 2 · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 6XBY · Cryo-EM structure of V-ATPase from bovine brain, state 2 · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 7UNE · The V1 region of bovine V-ATPase in complex with human mEAK7 (focused refinement) · an experimental structure of the same protein · chain A against N, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31404
- Elsewhere: UniProt P31404 · AlphaFold DB P31404
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