UniProt P31404
V-type proton ATPase catalytic subunit A (P31404)
V-type proton ATPase catalytic subunit A (UniProt P31404), EC 7.1.2.2: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P31404
- Protein
- V-type proton ATPase catalytic subunit A
- EC
- 7.1.2.2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 38 · 3 records with a druggable one
Structures
7 records of P31404 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6XBW | Cryo-EM structure of V-ATPase from bovine brain, state 1 | electron microscopy | A, B, C | MG, ADP | — |
| 6XBW | Cryo-EM structure of V-ATPase from bovine brain, state 1 | electron microscopy | A, B, C | MG, ADP | — |
| 6XBY | Cryo-EM structure of V-ATPase from bovine brain, state 2 | electron microscopy | A, B, C | MG, ADP | — |
| 7KHR | Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain | electron microscopy | A, B, C | MG, ADP | 11 (best 0.90) |
| 7KHR | Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain | electron microscopy | A, B, C | MG, ADP | — |
| 7UNE | The V1 region of bovine V-ATPase in complex with human mEAK7 (focused refinement) | electron microscopy | L, M, N | — | 17 (best 0.90) |
| P31404 | AlphaFold monomer V2.0 prediction for V-type proton ATPase catalytic subunit a (P31404) | predicted | A | — | 10 (best 0.51) |
Ligands
Experiment against prediction
- 6XBW chain B against the predicted model P31404: TM-score 0.99, RMSD 0.98 Å
- 6XBW chain B against the predicted model P31404: TM-score 0.99, RMSD 0.98 Å
- 6XBY chain C against the predicted model P31404: TM-score 0.99, RMSD 0.98 Å
- 7KHR chain B against the predicted model P31404: TM-score 0.99, RMSD 1.02 Å
- 7KHR chain B against the predicted model P31404: TM-score 0.99, RMSD 1.02 Å
- 6XBW chain C against the predicted model P31404: TM-score 0.99, RMSD 0.99 Å
- 6XBW chain C against the predicted model P31404: TM-score 0.99, RMSD 0.99 Å
- 6XBY chain A against the predicted model P31404: TM-score 0.99, RMSD 1.02 Å
- 7KHR chain C against the predicted model P31404: TM-score 0.98, RMSD 1.12 Å
- 7KHR chain C against the predicted model P31404: TM-score 0.98, RMSD 1.12 Å
Elsewhere
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