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AlphaFold monomer V2.0 prediction for acid-activated urea channel (P56874)

Analyse AlphaFold monomer V2.0 prediction for acid-activated urea channel (P56874) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P56874
Type
protein
Length
195 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xe8A815f214BD91816A95FA8f72fe02a140345800
Molecule
Acid-activated urea channel
UniProt
P56874
Pockets
2 · best druggability 0.71

Structure

1 distinct chain · 77% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAcid-activated urea channelprotein19577% helix, 2% strandP56874

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13980.710.8234empty
23520.690.8229empty

Compared structures

  • 6NSK · CryoEM structure of Helicobacter pylori urea channel in open state. · an experimental structure of the same protein · chain A against B, TM-score 0.91
  • 6NSK · Cryoem structure of helicobacter pylori urea channel in open state. · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 6NSJ · CryoEM structure of Helicobacter pylori urea channel in closed state · an experimental structure of the same protein · chain A against C, TM-score 0.88
  • 6NSJ · Cryoem structure of helicobacter pylori urea channel in closed state · an experimental structure of the same protein · chain A against A, TM-score 0.88

Analyse

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