Research workbench
AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1 (P46677)
Analyse AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P46677
- Type
- protein
- Length
- 1,066 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x362a6d063b1B7E1B6EfD3A9A7CA3612e3FE037AA
- Molecule
- Transcription initiation factor tfiid subunit 1
- UniProt
- P46677
- Pockets
- 12 · best druggability 0.71
Structure
1 distinct chain · 24% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor tfiid subunit 1 | protein | 1066 | 24% helix, 9% strand | P46677 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1142 | 0.71 | 0.75 | 77 | empty |
| 2 | 552 | 0.71 | 0.80 | 64 | empty |
| 3 | 189 | 0.60 | 0.81 | 24 | empty |
| 4 | 121 | 0.41 | 0.76 | 20 | empty |
| 5 | 107 | 0.38 | 0.75 | 14 | empty |
Compared structures
- 4OY2 · Crystal structure of TAF1-TAF7, a TFIID subcomplex · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 4OY2 · Crystal structure of TAF1-TAF7, a tfiid subcomplex · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 6E16 · Ternary structure of C-myc-tbp-TAF1 · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 4B0A · The high-resolution structure of ytbp-YTAF1 identifies conserved and competing… · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 4B0A · The high-resolution structure of yTBP-yTAF1 identifies conserved and competing… · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 6E24 · Ternary structure of C-myc-tbp-TAF1 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6E24 · Ternary structure of c-Myc-TBP-TAF1 · an experimental structure of the same protein · chain A against A, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46677
- Elsewhere: UniProt P46677 · AlphaFold DB P46677
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