Research workbench
AlphaFold monomer V2.0 prediction for SWI/SNF chromatin-remodeling complex subunit SWI1 (P09547)
Analyse AlphaFold monomer V2.0 prediction for SWI/SNF chromatin-remodeling complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P09547
- Type
- protein
- Length
- 1,314 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
- Molecule
- SWI/SNF chromatin-remodeling complex subunit SWI1
- UniProt
- P09547
- Pockets
- 15 · best druggability 0.73
Structure
1 distinct chain · 43% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SWI/SNF chromatin-remodeling complex subunit SWI1 | protein | 1314 | 43% helix, 1% strand | P09547 |
Pockets
15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1096 | 0.73 | 0.76 | 74 | empty |
| 2 | 444 | 0.61 | 0.76 | 40 | empty |
| 3 | 217 | 0.53 | 0.78 | 32 | empty |
| 4 | 214 | 0.53 | 0.77 | 27 | empty |
| 5 | 127 | 0.50 | 0.80 | 26 | empty |
Compared structures
- 7C4J · Cryo-EM structure of the yeast SWI/SNF complex in a nucleosome free state · an experimental structure of the same protein · chain A against I, TM-score 0.37
- 7C4J · Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state · an experimental structure of the same protein · chain A against I, TM-score 0.37
- 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 7EGP · The structure of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 7EGM · The SRM module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 7EGM · The srm module of SWI/SNF-nucleosome complex · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 6UXW · SWI/SNF nucleosome complex with ADP-BeFx · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 6UXV · SWI/SNF body module · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 6UXV · SWI/SNF Body Module · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 6UXW · SWI/SNF nucleosome complex with ADP-befx · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 1KN5 · Solution structure of arid domain of ADR6 from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 1KN5 · Solution structure of arid domain of ADR6 from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.07
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09547
- Elsewhere: UniProt P09547 · AlphaFold DB P09547
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