Research workbench
AlphaFold monomer V2.0 prediction for double-stranded RNA-binding protein staufen homolog 1 (O95793)
Analyse AlphaFold monomer V2.0 prediction for double-stranded RNA-binding protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O95793
- Type
- protein
- Length
- 577 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x378a28002909c2509a47F088Dee431D1ba770530
- Molecule
- Double-stranded RNA-binding protein staufen homolog 1
- UniProt
- O95793
- Pockets
- 3 · best druggability 0.49
Structure
1 distinct chain · 26% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Double-stranded RNA-binding protein staufen homolog 1 | protein | 577 | 26% helix, 15% strand | O95793 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.49 | 0.82 | 17 | empty |
| 2 | 207 | 0.45 | 0.74 | 21 | empty |
| 3 | 67 | 0.38 | 0.78 | 15 | empty |
Compared structures
- 6SDW · Solution structure of STAUFEN1 DSRBD3+4 - HARF1 sbs dsrna complex. · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 6SDW · Solution structure of Staufen1 dsRBD3+4 - hARF1 SBS dsRNA complex. · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 6HTU · Structure of hStau1 dsRBD3-4 in complex with ARF1 RNA · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 6HTU · Structure of HSTAU1 DSRBD3-4 in complex with ARF1 RNA · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 4DKK · The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 4DKK · The X-ray crystal structure of the human STAU1 ssm-'RBD'5 domain- swapped dimer · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 6SDY · Solution structure of Staufen1 dsRBD4 - hARF1 SBS dsRNA complex. · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 6SDY · Solution structure of STAUFEN1 DSRBD4 - HARF1 sbs dsrna complex. · an experimental structure of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95793
- Elsewhere: UniProt O95793 · AlphaFold DB O95793
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