UniProt O95793
Double-stranded RNA-binding protein Staufen homolog 1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1 (UniProt O95793): 7 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O95793
- Protein
- Double-stranded RNA-binding protein Staufen homolog 1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
8 records of O95793 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DKK | The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer | x-ray diffraction | A | — | — |
| 4DKK | The X-ray crystal structure of the human STAU1 ssm-'RBD'5 domain- swapped dimer | x-ray diffraction | A | — | — |
| 6HTU | Structure of hStau1 dsRBD3-4 in complex with ARF1 RNA | x-ray diffraction | A, B, C | — | — |
| 6HTU | Structure of HSTAU1 DSRBD3-4 in complex with ARF1 RNA | x-ray diffraction | A, B, C | — | — |
| 6SDW | Solution structure of Staufen1 dsRBD3+4 - hARF1 SBS dsRNA complex. | solution nmr | A | — | 2 (best 0.72) |
| 6SDW | Solution structure of STAUFEN1 DSRBD3+4 - HARF1 sbs dsrna complex. | solution nmr | A | — | — |
| 6SDY | Solution structure of STAUFEN1 DSRBD4 - HARF1 sbs dsrna complex. | solution nmr | A | — | — |
| O95793 | AlphaFold monomer V2.0 prediction for double-stranded RNA-binding protein staufen homolog 1 (O95793) | predicted | A | — | 3 (best 0.49) |
Experiment against prediction
- 6HTU chain A against the predicted model O95793: TM-score 0.93, RMSD 1.43 Å
- 6HTU chain A against the predicted model O95793: TM-score 0.93, RMSD 1.43 Å
- 6HTU chain C against the predicted model O95793: TM-score 0.89, RMSD 1.16 Å
- 6HTU chain C against the predicted model O95793: TM-score 0.89, RMSD 1.16 Å
- 6SDY chain A against the predicted model O95793: TM-score 0.71, RMSD 2.61 Å
- 4DKK chain A against the predicted model O95793: TM-score 0.63, RMSD 2.37 Å
- 4DKK chain A against the predicted model O95793: TM-score 0.63, RMSD 2.37 Å
- 6SDW chain A against the predicted model O95793: TM-score 0.51, RMSD 4.62 Å
- 6SDW chain A against the predicted model O95793: TM-score 0.51, RMSD 4.62 Å
Elsewhere
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