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AlphaFold monomer V2.0 prediction for DNA replication complex gins protein SLD5 (Q9BRT9)

Analyse AlphaFold monomer V2.0 prediction for DNA replication complex gins protein SLD5… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9BRT9
Type
protein
Length
223 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB797235589280D92Ce4bA47be78Fa8180f655a40
Molecule
DNA replication complex gins protein SLD5
UniProt
Q9BRT9
Pockets
2 · best druggability 0.51

Structure

1 distinct chain · 53% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA replication complex gins protein SLD5protein22353% helix, 11% strandQ9BRT9

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11870.510.7830empty
2570.310.7613empty

Compared structures

  • 7PFO · Core human replisome · an experimental structure of the same protein · chain A against G, TM-score 0.88
  • 7PLO · H. sapiens replisome-CUL2/LRR1 complex · an experimental structure of the same protein · chain A against G, TM-score 0.88
  • 8OK2 · Bipartite interaction of TOPBP1 with the GINS complex · an experimental structure of the same protein · chain A against D, TM-score 0.87
  • 6XTX · CryoEM structure of human CMG bound to ATPgammaS and DNA · an experimental structure of the same protein · chain A against D, TM-score 0.86
  • 6XTX · Cryoem structure of human cmg bound to atpgammas and DNA · an experimental structure of the same protein · chain A against D, TM-score 0.86
  • 6XTY · Cryoem structure of human cmg bound to and-1 (cmga) · an experimental structure of the same protein · chain A against D, TM-score 0.86
  • 2Q9Q · The crystal structure of full length human gins complex · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 2Q9Q · The crystal structure of full length human GINS complex · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 2E9X · The crystal structure of human gins core complex · an experimental structure of the same protein · chain A against D, TM-score 0.86
  • 2E9X · The crystal structure of human GINS core complex · an experimental structure of the same protein · chain A against D, TM-score 0.86
  • 8B9D · Human replisome bound by Pol Alpha · an experimental structure of the same protein · chain A against G, TM-score 0.85
  • 2EHO · Crystal structure of human GINS complex · an experimental structure of the same protein · chain A against I, TM-score 0.81

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