UniProt Q9BRT9
GINS complex subunit 4 (Q9BRT9)
GINS complex subunit 4 (UniProt Q9BRT9): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 66 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BRT9
- Protein
- GINS complex subunit 4
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 66 · 9 records with a druggable one
Structures
14 records of Q9BRT9 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E9X | The crystal structure of human GINS core complex | x-ray diffraction | D, H | SO4 | 15 (best 0.85) |
| 2E9X | The crystal structure of human gins core complex | x-ray diffraction | D, H | — | — |
| 2EHO | Crystal structure of human GINS complex | x-ray diffraction | A, E, I | SO4 | 15 (best 0.81) |
| 2EHO | Crystal structure of human gins complex | x-ray diffraction | A, E, I | — | — |
| 2Q9Q | The crystal structure of full length human GINS complex | x-ray diffraction | B, F | — | 16 (best 0.84) |
| 2Q9Q | The crystal structure of full length human gins complex | x-ray diffraction | B, F | — | — |
| 6XTX | CryoEM structure of human CMG bound to ATPgammaS and DNA | electron microscopy | D | — | 1 (best 0.87) |
| 6XTX | Cryoem structure of human cmg bound to atpgammas and DNA | electron microscopy | D | — | — |
| 6XTY | Cryoem structure of human cmg bound to and-1 (cmga) | electron microscopy | D | — | — |
| 7PFO | Core human replisome | electron microscopy | G | — | 3 (best 0.89) |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | G | — | 2 (best 0.90) |
| 8B9D | Human replisome bound by Pol Alpha | electron microscopy | G | — | 3 (best 0.85) |
| 8OK2 | Bipartite interaction of TOPBP1 with the GINS complex | electron microscopy | D | — | 9 (best 0.86) |
| Q9BRT9 | AlphaFold monomer V2.0 prediction for DNA replication complex gins protein SLD5 (Q9BRT9) | predicted | A | — | 2 (best 0.51) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 2Q9Q chain B against the predicted model Q9BRT9: TM-score 0.97, RMSD 1.05 Å
- 2Q9Q chain B against the predicted model Q9BRT9: TM-score 0.97, RMSD 1.05 Å
- 2EHO chain A against the predicted model Q9BRT9: TM-score 0.97, RMSD 0.87 Å
- 2EHO chain A against the predicted model Q9BRT9: TM-score 0.97, RMSD 0.87 Å
- 2E9X chain D against the predicted model Q9BRT9: TM-score 0.97, RMSD 1.16 Å
- 2E9X chain D against the predicted model Q9BRT9: TM-score 0.97, RMSD 1.16 Å
- 7PFO chain G against the predicted model Q9BRT9: TM-score 0.96, RMSD 1.19 Å
- 7PLO chain G against the predicted model Q9BRT9: TM-score 0.96, RMSD 1.21 Å
- 8OK2 chain D against the predicted model Q9BRT9: TM-score 0.95, RMSD 1.48 Å
- 6XTX chain D against the predicted model Q9BRT9: TM-score 0.94, RMSD 1.41 Å
Elsewhere
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