Research workbench
AlphaFold monomer V2.0 prediction for splicing factor 3A subunit 2 (Q15428)
Analyse AlphaFold monomer V2.0 prediction for splicing factor 3A subunit 2 (Q15428) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q15428
- Type
- protein
- Length
- 464 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5Cc8336db6d496E3B01007Aa23AcE4A695b4613E
- Molecule
- Splicing factor 3A subunit 2
- UniProt
- Q15428
- Pockets
- 1 · best druggability 0.31
Structure
1 distinct chain · 10% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Splicing factor 3A subunit 2 | protein | 464 | 10% helix, 13% strand | Q15428 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 83 | 0.31 | 0.73 | 12 | empty |
Compared structures
- 6QX9 · Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). · an experimental structure of the same protein · chain A against A2, TM-score 0.27
- 8QO9 · Cryo-EM structure of a human spliceosomal B complex protomer · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8QZS · Cryo-EM structure of the cross-exon B-like complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8R09 · Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8QXD · Cryo-EM structure of the cross-exon pre-B complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8R08 · Cryo-EM structure of the cross-exon pre-B+AMPPNP complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8RM5 · Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8R0A · Cryo-EM structure of the cross-exon pre-B+5'ss complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 8R0B · Cryo-EM structure of the cross-exon pre-B+ATP complex · an experimental structure of the same protein · chain A against 8, TM-score 0.19
- 7VPX · The cryo-EM structure of the human pre-A complex · an experimental structure of the same protein · chain A against B, TM-score 0.19
- 7EVO · The cryo-EM structure of the human 17S U2 snrnp · an experimental structure of the same protein · chain A against B, TM-score 0.19
- 7EVO · The cryo-EM structure of the human 17S U2 snRNP · an experimental structure of the same protein · chain A against B, TM-score 0.19
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15428
- Elsewhere: UniProt Q15428 · AlphaFold DB Q15428
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