Research workbench
AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein 2 (Q04002)
Analyse AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q04002
- Type
- protein
- Length
- 1,493 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x16e07C76957A2F24F14ACC5393e231dF9b8720B9
- Molecule
- Sister chromatid cohesion protein 2
- UniProt
- Q04002
- Pockets
- 15 · best druggability 0.73
Structure
1 distinct chain · 67% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sister chromatid cohesion protein 2 | protein | 1493 | 67% helix, 2% strand | Q04002 |
Pockets
15 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 804 | 0.73 | 0.78 | 69 | empty |
| 2 | 174 | 0.51 | 0.78 | 28 | empty |
| 3 | 106 | 0.47 | 0.80 | 15 | empty |
| 4 | 194 | 0.45 | 0.74 | 30 | empty |
| 5 | 145 | 0.43 | 0.75 | 23 | empty |
Compared structures
- 6ZZ6 · Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex · an experimental structure of the same protein · chain A against D, TM-score 0.66
- 6ZZ6 · Cryo-EM structure of S.CEREVISIAE cohesin-SCC2-DNA complex · an experimental structure of the same protein · chain A against D, TM-score 0.66
- 5W94 · Crystal structure of SCC4 in complex with SCC2N and CTF19N · an experimental structure of the same protein · chain A against D, TM-score 0.06
- 5W94 · Crystal structure of Scc4 in complex with Scc2n and Ctf19n · an experimental structure of the same protein · chain A against D, TM-score 0.06
- 4XDN · Crystal structure of SCC4 in complex with SCC2N · an experimental structure of the same protein · chain A against B, TM-score 0.06
- 4XDN · Crystal structure of Scc4 in complex with Scc2n · an experimental structure of the same protein · chain A against B, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q04002
- Elsewhere: UniProt Q04002 · AlphaFold DB Q04002
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