Research workbench
AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein 2 (Q750S2)
Analyse AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q750S2
- Type
- protein
- Length
- 1,479 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xAdBb5c32E453244bFe88dA9295e60cB3604b64E1
- Molecule
- Sister chromatid cohesion protein 2
- UniProt
- Q750S2
- Pockets
- 15 · best druggability 0.66
Structure
1 distinct chain · 69% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sister chromatid cohesion protein 2 | protein | 1479 | 69% helix, 1% strand | Q750S2 |
Pockets
15 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 548 | 0.66 | 0.77 | 50 | empty |
| 2 | 98 | 0.59 | 0.87 | 29 | empty |
| 3 | 280 | 0.59 | 0.78 | 39 | empty |
| 4 | 220 | 0.56 | 0.78 | 27 | empty |
| 5 | 125 | 0.52 | 0.81 | 19 | empty |
Compared structures
- 5ME3 · Structure of the Scc2 C-terminus · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 5ME3 · Structure of the SCC2 C-terminus · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 5C6G · Structural Insights into the Scc2-Scc4 Cohesin Loader · an experimental structure of the same protein · chain A against D, TM-score 0.06
- 5C6G · Structural insights into the SCC2-SCC4 cohesin loader · an experimental structure of the same protein · chain A against D, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q750S2
- Elsewhere: UniProt Q750S2 · AlphaFold DB Q750S2
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