UniProt Q750S2
Sister chromatid cohesion protein 2 (Q750S2)
Sister chromatid cohesion protein 2 (UniProt Q750S2): 4 experimental structures and 1 predicted model on GenesisL1, 79 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q750S2
- Protein
- Sister chromatid cohesion protein 2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 79 · 5 records with a druggable one
Structures
5 records of Q750S2 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5C6G | Structural Insights into the Scc2-Scc4 Cohesin Loader | x-ray diffraction | B, D | — | 12 (best 0.78) |
| 5C6G | Structural insights into the SCC2-SCC4 cohesin loader | x-ray diffraction | B, D | — | 12 (best 0.78) |
| 5ME3 | Structure of the Scc2 C-terminus | x-ray diffraction | A, B | — | 20 (best 0.70) |
| 5ME3 | Structure of the SCC2 C-terminus | x-ray diffraction | A, B | — | 20 (best 0.70) |
| Q750S2 | AlphaFold monomer V2.0 prediction for sister chromatid cohesion protein 2 (Q750S2) | predicted | A | — | 15 (best 0.66) |
Experiment against prediction
- 5ME3 chain A against the predicted model Q750S2: TM-score 0.79, RMSD 5.58 Å
- 5ME3 chain A against the predicted model Q750S2: TM-score 0.79, RMSD 5.58 Å
- 5ME3 chain B against the predicted model Q750S2: TM-score 0.78, RMSD 5.78 Å
- 5ME3 chain B against the predicted model Q750S2: TM-score 0.78, RMSD 5.78 Å
- 5C6G chain D against the predicted model Q750S2: TM-score 0.41, RMSD 5.14 Å
- 5C6G chain D against the predicted model Q750S2: TM-score 0.41, RMSD 5.14 Å
- 5C6G chain B against the predicted model Q750S2: TM-score 0.38, RMSD 5.19 Å
- 5C6G chain B against the predicted model Q750S2: TM-score 0.38, RMSD 5.19 Å
Elsewhere
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