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AlphaFold monomer V2.0 prediction for squamous cell carcinoma antigen recognized by T-cells 3 (Q15020)

Analyse AlphaFold monomer V2.0 prediction for squamous cell carcinoma antigen… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q15020
Type
protein
Length
963 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf498a07CB267aF7A6C8376eAc13c07Cb31bc9C20
Molecule
Squamous cell carcinoma antigen recognized by T-cells 3
UniProt
Q15020
Pockets
5 · best druggability 0.66

Structure

1 distinct chain · 50% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASquamous cell carcinoma antigen recognized by T-cells 3protein96350% helix, 7% strandQ15020

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16270.660.7666empty
23580.570.7546empty
31970.520.7721empty
4540.320.7615empty
5700.300.7313empty

Compared structures

  • 5CTQ · Crystal structure of human SART3/TIP110 half-a tpr (hat) domain · an experimental structure of the same protein · chain A against A, TM-score 0.52
  • 5JPZ · Crystal structure of hat domain of human squamous cell carcinoma antigen recognized by T… · an experimental structure of the same protein · chain A against B, TM-score 0.50
  • 5JPZ · Crystal structure of HAT domain of human Squamous Cell Carcinoma Antigen Recognized By T… · an experimental structure of the same protein · chain A against B, TM-score 0.50
  • 5CTR · Crystal structure of human SART3 hat-C domain-human USP4 dusp-ubl domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.32
  • 5CTR · Crystal structure of human SART3 HAT-C domain-human USP4 DUSP-UBL domain complex · an experimental structure of the same protein · chain A against A, TM-score 0.32

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