MolNFT v1 · #123617 · protein
Crystal structure of hat domain of human squamous cell carcinoma antigen recognized by T cells 3, SART3 (TIP110)
5JPZ · Squamous cell carcinoma antigen recognized by T-cells 3: “Crystal structure of hat domain of human squamous cell carcinoma antigen recognized by T cells 3, SART3…”. X-ray diffraction, 12 pockets (best druggability 0.73). MolNFT v1…
- PDB
- 5JPZ
- Type
- protein
- Length
- 968 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Squamous cell carcinoma antigen recognized by T-cells 3
- UniProt
- Q15020
- Pockets
- 12 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Squamous cell carcinoma antigen recognized by T-cells 3 | protein | 483 | 76% helix, 0% strand | Q15020 |
| B | Squamous cell carcinoma antigen recognized by T-cells 3 | protein | 485 | 76% helix, 0% strand | Q15020 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 800 | 0.73 | 0.78 | 73 | empty |
| 2 | 255 | 0.56 | 0.77 | 32 | empty |
| 3 | 203 | 0.54 | 0.78 | 23 | empty |
| 4 | 258 | 0.53 | 0.75 | 43 | empty |
| 5 | 216 | 0.53 | 0.77 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1565 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 5JPZ · Crystal structure of HAT domain of human Squamous Cell Carcinoma Antigen Recognized By T… · the same entry in another collection · chain A against A, TM-score 1.00
- Q15020 · AlphaFold monomer V2.0 prediction for squamous cell carcinoma antigen recognized by… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15020
- Elsewhere: RCSB PDB 5JPZ · PDBe 5JPZ · UniProt Q15020
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.