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AlphaFold monomer V2.0 prediction for RAS-related GTP-binding protein C (Q9HB90)

Analyse AlphaFold monomer V2.0 prediction for RAS-related GTP-binding protein C (Q9HB90) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9HB90
Type
protein
Length
399 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
Molecule
RAS-related GTP-binding protein C
UniProt
Q9HB90
Pockets
3 · best druggability 0.51

Structure

1 distinct chain · 36% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARAS-related GTP-binding protein Cprotein39936% helix, 17% strandQ9HB90

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11310.510.8022empty
21690.430.7425empty
3560.320.7718empty

Compared structures

  • 6ULG · Cryo-EM structure of the flcn-FNIP2-rag-ragulator complex · an experimental structure of the same protein · chain A against G, TM-score 0.76
  • 6ULG · Cryo-EM structure of the FLCN-FNIP2-Rag-Ragulator complex · an experimental structure of the same protein · chain A against G, TM-score 0.76
  • 6WJ3 · CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state · an experimental structure of the same protein · chain A against G, TM-score 0.75
  • 6WJ3 · Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the post-gap state · an experimental structure of the same protein · chain A against G, TM-score 0.75
  • 6WJ2 · Cryoem structure of the SLC38A9-raga-ragc-ragulator complex in the pre-gap state · an experimental structure of the same protein · chain A against G, TM-score 0.75
  • 6WJ2 · CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state · an experimental structure of the same protein · chain A against G, TM-score 0.75
  • 8DHB · Active FLCN GAP complex · an experimental structure of the same protein · chain A against A, TM-score 0.75
  • 7T3B · GATOR1-rag-ragulator - gap complex · an experimental structure of the same protein · chain A against E, TM-score 0.74
  • 7T3B · GATOR1-RAG-RAGULATOR - GAP Complex · an experimental structure of the same protein · chain A against E, TM-score 0.74
  • 6NZD · Cryo-EM structure of the lysosomal folliculin complex (flcn-FNIP2- raga-ragc-ragulator) · an experimental structure of the same protein · chain A against G, TM-score 0.73
  • 6NZD · Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) · an experimental structure of the same protein · chain A against G, TM-score 0.73
  • 7T3C · GATOR1-rag-ragulator - dual complex · an experimental structure of the same protein · chain A against E, TM-score 0.73

Analyse

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